Chemical Imbalances Due to Depression

A new look at depression: challenging the chemical imbalance model of depression.

For over three decades, scientists have attributed a chemical imbalance in the brain as the source of major depression. Now, a new study provides an explanation of how this “chemical imbalance” occurs. Major depression is a disease that...
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(This article was first printed in Understanding Depression, a Special Health Report from Harvard Medical School.) It's often said that depression results from a chemical imbalance, but that figure of speech doesn't capture how complex the disease is...
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What's behind perpetually lousy moods.